@FierceBiotech: Between 4Q07 and 4Q09, 25 percent of US public biotechs disappeared (half via M&A), says BIO. | Follow @FierceBiotech

 @JohnCFierce: For sale: Ark Therapeutics. Willing to consider any serious offer. Buyer must be willing to mount new Ph3 for lead drug. Follow @JohnCFierce

> San Diego-based Tocagen has raised almost $7.8 million from 75 investors in a Series D round of financing. Article

> The FDA has granted ISTA Pharmaceuticals NDA for XiDay a PDUFA date of October 16, 2010. The company's request for a shorter, six-month priority review is still under consideration by the agency. ISTA release

> INSYS Therapeutics announced positive results from the pivotal phase III efficacy trial for patients utilizing the Fentanyl Sublingual Spray (SL Spray) technology to treat breakthrough cancer pain. INSYS release

> Amgen plans to sell $1 billion of senior notes in a two-part sale, reported IFR, a Thomson Reuters service. Report

> Stirling Pharma, an Australian group, has taken over North Sydney-based Keata Pharma for about $3.6 million. Report

And Finally... More than 100 researchers teamed up over two years pieced together a genetic blueprint of the bacteria that's found in the human digestive tract. Article